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Xeljanz, also known as tofacitinib, is a medication approved by the US Food and Drug Administration (FDA) for treating rheumatoid arthritis (RA) and ulcerative colitis (UC). This article will provide you with important information about xeljanz, its uses, and potential side effects.

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What is Xeljanz?

Xeljanz is a prescription medication that belongs to a class of drugs known as Janus kinase (JAK) inhibitors. It works by blocking certain proteins in the body that contribute to inflammation. This makes it an effective treatment for RA and UC, which are both autoimmune disorders characterized by chronic inflammation.

How is Xeljanz Used for RA?

Xeljanz is used for the treatment of moderate to severe RA in adults who have not responded well to or cannot tolerate other medications such as methotrexate. It can be used alone or in combination with methotrexate. Xeljanz comes in both extended-release tablets and an oral solution and is typically taken twice a day.

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How is Xeljanz Used for UC?

Xeljanz is also approved for the treatment of moderate to severe UC in adults who have not responded well to other therapies. It is typically used after other medications, such as corticosteroids, have been unsuccessful. Xeljanz is taken as a tablet twice a day and works by reducing inflammation in the colon and rectum.

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Side Effects of Xeljanz

While xeljanz can be an effective treatment for RA and UC, it does come with potential side effects. Common side effects may include headache, diarrhea, and upper respiratory tract infections. More serious side effects may include increased risk of infections, liver problems, and blood clots. It is important to discuss potential side effects with your doctor before starting Xeljanz treatment.

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Considerations Before Taking Xeljanz

Before taking xeljanz, it is important to inform your doctor about any other medications you are taking, including vitamins and supplements. This is because xeljanz may interact with certain medications, such as antifungal drugs and live vaccines. It is also important to tell your doctor if you have a history of infections, liver or kidney disease, or any other medical conditions. Xeljanz may not be suitable for individuals with certain pre-existing conditions.

Summary

• Xeljanz is a medication approved by the FDA for treating RA and UC.
• It is a JAK inhibitor that works by reducing inflammation in the body.
• Xeljanz is taken twice a day either as extended-release tablets or an oral solution.
• Common side effects may include headache, diarrhea, and upper respiratory tract infections.
• Xeljanz may interact with other medications and is not suitable for individuals with certain medical conditions.