Bo Nix, Broncos: Bo Nix is truly making a name for himself in the NFL. He has scored at least 16 points in five straight games and seven of his last eight. This week, facing the Cleveland Browns who have surrendered nearly 19 points per game to opposing quarterbacks, Nix has a great opportunity to continue his scoring streak.
Derek Carr, Saints: After a bye week, Carr is back with fresh legs. He had scored at least 18 points in two straight games prior to the bye. Now, playing against a Rams team that has given up 16 or more points to opposing QBs in four of its last five, Carr should be able to put up some solid numbers.
Brock Purdy, 49ers: Despite the 49ers head coach Kyle Shanahan's assurances that Purdy's injury is not long term, a matchup with the Buffalo Bills is not an ideal return. Until the 49ers figure out their offensive issues, starting Purdy against such a tough opponent is not a smart move.
Caleb Williams, Bears: While Williams had a great game against the Minnesota Vikings last week, the Lions present a much tougher challenge. They have surrendered the third-fewest points per game to quarterbacks all season and haven't allowed a quarterback to score more than 12 fantasy points in four straight games.
Jaylen Warren, Steelers: Although Warren is seeing fewer carries than Najee Harris, he has been the more efficient back lately. As the Steelers push for an AFC North title, Warren's usage is likely to increase. And with the Cincinnati Bengals surrendering four rushing touchdowns in their last three games, Warren is a must-start in 12-team leagues.
Rico Dowdle, Cowboys: The New York Giants allowed the Tampa Bay Buccaneers to score four rushing touchdowns with different players. Dowdle commanded 22 of Dallas' 26 backfield touches on Sunday. Just imagine what he can do with more opportunities.
D’Andre Swift, Bears: The Lions are a tough matchup for running backs. They have gone two straight games allowing fewer than 40 total rushing yards and have been great at preventing halfbacks from catching passes. With opposing running backs tallying three or fewer receptions in five of the last six games, Swift's ceiling is too low to start.
James Conner, Cardinals: The Minnesota Vikings have been very tough against running backs recently. Prior to Week 12, they had allowed only 14 non-PPR points combined to opposing running backs between Weeks 9 and 11. Conner was inefficient in Week 12 and his role may have been reduced to Trey Benson. Facing the Vikings, his ceiling is lower than usual.
Tank Dell, Texans: The return of Nico Collins has boosted Tank Dell's value. In Week 13, he faces a Jaguars' defense that allowed Houston's receivers to have a big game in Week 4. With the Jags likely to key in on Collins, Dell will have a little more space to make plays.
DeVonta Smith, Eagles: Smith has been dealing with an injury but if he can play in Week 13, he will have a great matchup against the Baltimore Ravens. He was great before his injury and the week of rest could have done him good.
Cedric Tillman, Browns: Tillman's injury kept him out of the end of Thursday night's game. Even without the injury, it seems his role is diminishing as Jerry Jeudy and Elijah Moore have seen more targets. Facing a tough Denver secondary in Week 13, Tillman is likely to be a third option and won't see much fantasy production.
Amari Cooper, Bills: Cooper has struggled since joining the Bills. Even with the bye week, the San Francisco 49ers have been tough on opposing wide receivers. They have allowed fewer than 20 non-PPR points to wideouts in four of their last five and seven of their last nine games. Expect the Bills to rely more on James Cook.
Cade Otton, Buccaneers: Otton didn't get much work in Week 12, but facing the Carolina Panthers in Week 13, he has earned a little leeway. Prior to Week 12, he had earned at least six targets in seven of his previous eight games. And the Panthers have allowed the most non-PPR points to tight ends all season.
Pat Freiermuth, Steelers: The Cincinnati Bengals have allowed opposing tight ends to score in each of the last three games and four of the last five. Freiermuth should be started considering this and his potential for production.
Mark Andrews, Ravens: Andrews has been inconsistent all season and a matchup against the Philadelphia Eagles won't help. The Eagles have only allowed more than 60 yards to opposing tight ends twice all year and only given up one touchdown to tight ends.
Kyle Pitts, Falcons: Fantasy players have been disappointed in Pitts lately. He has only corralled one pass in two of his last three games. The Los Angeles Chargers had not allowed a touchdown to opposing tight ends all year and only allowed double-digit non-PPR points once to tight ends. Pitts is not at that level yet.