Global Study Links Ultra-Processed Foods to Rising Premature Deaths

Apr 29, 2025 at 12:19 PM

A groundbreaking study conducted across eight nations reveals a startling connection between the consumption of ultra-processed foods (UPFs) and an increase in premature mortality rates. Researchers found that for every 10% rise in UPF intake as part of total energy consumption, there is a corresponding 3% increase in all-cause mortality risk. Countries with higher levels of UPF consumption, such as the United States, experience up to 14% of preventable deaths linked directly to these food items. The findings underscore the necessity for comprehensive global policies aimed at promoting healthier dietary habits centered on fresh, minimally processed ingredients.

The research, spearheaded by Dr. Eduardo Augusto Fernandes Nilson from Brazil's Oswaldo Cruz Foundation, examined data from nationally representative dietary surveys and mortality statistics spanning Australia, Brazil, Canada, Chile, Colombia, Mexico, the United Kingdom, and the United States. UPFs, characterized by their industrial formulation using extracted or synthetic ingredients with minimal whole food content, have progressively replaced traditional meals. Dr. Nilson highlighted that the health impacts extend beyond critical nutrient contents like sodium, trans fats, and sugar due to changes during processing and artificial additives.

This investigation marks a shift from previous studies focusing solely on specific dietary risk factors toward analyzing broader food patterns influenced by industrial processing. Through advanced modeling techniques, the team established a linear association: each 10% increment in UPF dietary share correlates with a 3% heightened risk of death from any cause. Applying this model to national consumption data revealed significant variations—ranging from 4% in lower-consumption countries like Colombia to nearly 14% in high-consumption regions like the U.S.

For instance, it was estimated that in 2018 alone, approximately 124,000 premature deaths in the United States could be attributed to UPF consumption. Moreover, extensive links exist between high UPF intake and various diseases, including cardiovascular issues, obesity, diabetes, certain cancers, and even mental health disorders like depression. This study represents the first attempt to quantify the global burden of UPF-related premature mortality across different settings, emphasizing its significance as a public nutrition priority worldwide.

Dr. Nilson expressed concern over the rising trend of UPF consumption in low- and middle-income countries, where adoption continues to grow despite relatively stable levels in wealthier nations. He advocated for urgent policy interventions globally to discourage UPF consumption and encourage traditional diets rich in local fresh and minimally processed foods.

The implications of this study extend far beyond individual health choices, calling for systemic changes in how societies approach food production and consumption. By addressing the pervasive presence of ultra-processed foods, policymakers can potentially mitigate substantial portions of preventable disease burdens affecting populations worldwide. Promoting sustainable, nutritious eating habits becomes not only a matter of personal well-being but also a crucial element of global public health strategies moving forward.