MYworldfix

A groundbreaking study, known as EXERT, has uncovered promising evidence indicating that both low and moderate-high intensity physical activities can significantly contribute to preserving cognitive abilities among older adults experiencing mild memory issues. This population is particularly vulnerable, as they are at an elevated risk of developing Alzheimer’s disease. Conducted over a year, the research demonstrated that participants engaging in either form of exercise experienced notably reduced cognitive deterioration and diminished brain volume loss, especially within the prefrontal cortex, compared to those receiving standard care.

This investigation underscores the potential of accessible, community-integrated fitness programs for individuals susceptible to dementia. Remarkably, even less strenuous activities such as stretching and balance exercises have proven effective in decelerating cognitive decline, suggesting a practical pathway toward enhanced brain health. The trial's collaboration with local YMCAs exemplifies its real-world applicability.

Researchers from the University of California San Diego and Wake Forest University conducted this extensive study, which was published in two papers featured in Alzheimer’s and Dementia: The Journal of the Alzheimer’s Association. The EXERT study evaluated the impact of varying exercise intensities on sedentary older adults with amnestic mild cognitive impairment (MCI), a significant precursor to Alzheimer’s dementia. Their findings revealed that both low and moderate-high intensity workouts maintained cognitive stability over 12 months, with participants showing less brain volume reduction, particularly in the prefrontal cortex.

Dr. Aladdin Shadyab, lead author of one of the new papers, highlighted the critical timing of intervention within this demographic. "This group doesn't yet have dementia but faces a very high risk," he noted. "Our findings suggest that even low-intensity exercise might mitigate cognitive decline in older adults predisposed to such conditions." Previous studies had suggested the benefits of exercise on cognitive health, yet conclusive evidence remained elusive until now.

The EXERT study innovatively partnered with YMCA facilities to bring the intervention closer to participants' homes, enhancing community implementation possibilities. Approximately 300 inactive older adults with MCI were randomly assigned to either moderate-high intensity aerobic training or lower-intensity stretching and balance activities. Under YMCA trainers' supervision, these participants exercised three to four times weekly for a year, undergoing regular assessments of cognitive function and brain volume.

Dr. Laura Baker, principal investigator of the EXERT study, described it as a landmark endeavor due to its scale and rigor. "While we anticipated further cognitive decline, we found stability across both exercise groups during the study period," she remarked. This outcome implies that both lower and higher intensity exercise may effectively slow cognitive deterioration. Additionally, participating in the research itself, irrespective of treatment type, might offer protective effects against cognitive decline due to intellectual and social engagement.

In conclusion, these comprehensive findings propose that exercise represents a viable, safe, and feasible strategy to promote brain health and prevent ongoing cognitive decline in older adults with MCI. Dr. Shadyab emphasized the promise these results hold for those at high dementia risk, stating, "Regular exercise, even at low intensity, could substantially assist older adults in slowing or delaying cognitive decline." Thus, this study marks a significant advancement in understanding how physical activity can positively influence aging brains.